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KMID : 0613620180380010421
Health Social Welfare Review
2018 Volume.38 No. 1 p.421 ~ p.458
Cost Effectiveness Analysis of Seoul Metropolitan City¡¯s Hepatitis A Vaccination Program for North Korean Defectors
Park Se-Hee

Kim Sun-Young
Lee Tae-Jin
Abstract
North Korean Defectors (NKDs) are estimated to be vulnerable to health issues due to the experience of food shortage in North Kora as well as the problems they face after escaping from North Korea. The healthcare programs targeting NKDs are required to improve their health outcomes and help reduce health inequalities between NKDs and South Koreans. The objective of this study was to conduct cost-effective analysis of hepatitis A (HAV) vaccination program for NKDs performed by Seoul City in order to make suggestions as to how to manage and expand healthcare programs for NKDs. A cost-effectiveness analysis was carried out, taking into consideration NKDs¡¯ age distribution, HAV immunity, and the prevalence of chronic hepatitis. A decision tree with Markov model was developed and NKDs were allocated to enter the Markov model based on their compliance with antibody test, 1st and 2nd HAV vaccination. In comparison to no vaccination program, HAV vaccination program led to incremental cost of 22,708 won and incremental effectiveness of 0.0005 QALY, resulting in ICER of 45,452,128 won/QALY. The subgroup analysis results indicated that the vaccination program was most cost-effective for those who suffer from chronic hepatitis and have no HAV immunity. In order to develop healthcare programs for NKDs, it would be recommended not only to consider the target population¡¯s characteristics, but also to find the vulnerable subgroups that benefit from the healthcare program and encourage them to comply with the program.
KEYWORD
North Korean Defectors, Hepatitis A, Vaccination Program, Cost-Effectiveness Analysis, CEA
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